Profacgen provides a comprehensive panel of services for the study of protein-protein interactions, of which the Bio-layer Interferometry (BLI) analysis is commonly used by our customers for the quantitative and qualitative characterization of biomolecule interactions and other applications. https://www.profacgen.com/bio-....layer-interferometry
Bacteria are the most widely used protein expression systems for their rapid growth, high yield, ease of manipulation and scale-up. The most widely used bacteria host is of course Escherichia coli. https://www.profacgen.com/bacteria-expression.htm
The variable domains (Fvs) of the heavy and light chain are of special interest in structural modeling, as they typically impart most or all of the specificity of an antibody for its antigen target. https://www.profacgen.com/Antibody-Modeling.htm
The characterization of Absorption, Distribution, Metabolism, and Excretion (also known as ADME) and Toxicity are essential steps in drug development. https://www.profacgen.com/adme-tox-prediction.htm
